Nicotinamide riboside klori, nicotinamide riboside
Nicotinamide Riboside Chloride is a newly appreciated form of Vitamin B3, with unique properties, it is a formal precursor of NAD+. Nicotinamide riboside (NR), first described in 1944 as a growth factor (Factor V) for Haemophilus influenza, and in 1951, NR, first investigated as a metabolic fate in Tisi mamifè .
Sinonim
Nicotinamideribosidechloride; Nicotinamideb-DriboSideChloride (WX900111); NicotinAmideriboside . Cl; Nicotimideribosidechloride; Piridinium, 3- (aminocarbonyl) -1- - d-ribofuranosyl-, klori (1: 1); 3- carbamoychemicalbookl -1- ((2r, 3r, 4s, 5r) -3, 4- dihydroxy {-5- (hydroxymethyl) tetrahydrofuran -2- yl) piridin -1- iumchlorid; 3- carbamoyl -1- (-d -ribofuranosyl) piridiniumchloride; 3- carbamoyl -1- beta-d-ribofuranosylpyridiniumchloride
● CAS NON .: 23111-00-4
● EC Non .: 200-184-4
● MF: C11H15N2O 5. Cl
● MW: 290.7
Paramèt nan nicotinamide riboside klori, nicotinamide riboside
|
Sijè |
Estanda |
Rezilta |
|
Aparisyon |
Poud blan |
Konfòm |
|
Idantifikasyon |
H-NMR |
Konfòm |
|
Pèt sou siye |
Mwens pase oswa egal a 2.0% |
0.78% |
|
Rezidi sou ignisyon |
Mwens pase oswa egal a 0.5% |
0.15% |
|
Metal lou |
Mwens pase oswa egal a 20ppm |
< 20 ppm |
|
Plon (PB) |
Mwens pase oswa egal a 1.5ppm |
Pa detekte |
|
Kadmyòm (CD) |
Mwens pase oswa egal a 0.18ppm |
Pa detekte |
|
Mèki (Hg) |
Mwens pase oswa egal a 0.002ppm |
Pa detekte |
|
Asenik (AS) |
Mwens pase oswa egal a 0.01ppm |
Pa detekte |
|
Kolifòm |
100cfu/g max |
Konfòm |
|
E . coli |
Negatif/10g |
Konfòm |
|
Salmonèl |
Negatif/25g |
Konfòm |
|
Staphylococcus |
Negatif/10g |
Konfòm |
|
Konte plak total |
100cfu/g max |
Konfòm |
|
Ledven ak mwazi |
100cfu/g max |
Konfòm |
|
Metanòl |
Mwens pase oswa egal a 10ppm |
Konfòm |
|
Pite pa HPLC |
Pi gran pase oswa egal a 98% |
99.5% |
● Anbalaj: 100g/sak; 500g/sak; 1kg/sak; 25kg/tanbou
● Metòd depo rekòmande: magazen nan yon kote fre, sèk ak ayere .
● Rekòmande tanperati depo: 2-8 degre
● Itilizasyon pwodwi: sipleman dyetetik
Benefis nan klori ribosid nicotinamide
Ede jenerasyon enèji
Nan bèt, nicotinamide riboside klori sipleman redwi konsomasyon NAD, ki amelyore fonksyon mitokondriyo, rapidman retabli mas nan misk, ak konsève nivo fòs NAD ak egzèsis volim nan pi gran sourit .
Amelyore fonksyon mantal
NR prezève selil yo nè nan sèvo a pa aktive SIRT3 a ak sipleman stimul wout yo NAD epi li ede anpeche koripsyon nan tèt ou .
Pwoteje fwa a
Pran NR oralman ogmante NAD nan kò a, ki ede pwoteje fwa a . Anplis de sa, NR te kapab pwolonje lonjevite, ogmante metabolis, sipòte batay la kont kansè, diminye sentòm dyabetik, ogmante metabolis, ka ede ak pèdi pwa .}
Anpeche pèt tande
Pa aktive chemen an SIRT3, yon etid UNC te jwenn li te ede pwoteje rat kont bri-induit pèt tande .
Poukisa nicotinamide riboside klori (NR) deziyen kòm yon natif natal NAD+ précurseur vitamin envètebre?
● Haemophilus grip se entèdi depann sou NR, NMN, oswa NAD+ pou kwasans nan san an lame .
● Lèt se yon sous NR .
● NR pwoteje newòn murin DRG .
● Exogenously te ajoute NR ak dérivés ogmante NAD+ akimilasyon nan liy selil imen .
● Candida glabrata itilize NR pandan enfeksyon distribiye .